Synthetic & Organic Chemist Job at OHR, San Diego, CA

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  • OHR
  • San Diego, CA

Job Description

Company Description

OHR uses primordial chemistry and synthetic biology to fashion strategic chemicals. Our technology enables the creation of carbon chains of deterministic length without cells, co-factors, or typical oil contaminants. With a core value of sustainability, OHR is focused on disrupting the petroleum industry through innovative solutions.

Role Description

Ohr Synbiosis is seeking an experienced Synthetic Organic and/or Process Development R&D Chemist in it's San Diego R&D lab. The candidate will spearhead chemical reaction discovery and chemical process development to convert biologically-derived intermediates into sustainable, industrial chemical products. The candidate will need to perform both in lab experiments and detailed dry-lab planning.

Responsibilities

  • Design and demonstrate novel multistep chemical syntheses to produce Ohr’s target compounds.
  • Perform discovery reactions with full characterization of all byproducts to quantify reaction performance.
  • Implement HPLC, GC, MS, TGA, and other relevant analytical techniques to determine reaction products and byproducts.
  • Perform reaction optimization DBTL cycles to optimize: conversion, yield, solvent selection, operating conditions, and product recovery.
  • Identify and apply heterogeneous catalysts for diverse reactions.
  • Identify appropriate equipment needed for Ohr to expand its R&D and Pilot Lab Chemistry footprint.
  • Perform heterogeneous hydrogenation and hydrodeoxygenation reaction discovery and process development.
  • Identify and evaluate appropriate industrial protection groups amendable to massive-scale production.
  • Perform aromatic modification reaction discovery and development.
  • Evaluate and implement chemical process product purification techniques including crystallization, liquid-liquid extraction, precipitation, filtration, and distillation.
  • Scale product recovery techniques to Pilot Lab unit operations.
  • Leverage knowledge of organic chemistry to design multistep synthetic routes that maintain carbon skeletons and stabilize molecules.
  • Apply knowledge of both batch and flow chemistry to develop novel reactions and optimize conditions.
  • Lead interactions with CROs, in parallel with in-house experiments, to rapidly develop chemical processes and to gather additional analytical datasets.
  • Exemplify excellence in lab safety and chemical hygiene practices.
  • Strengthen and expand both chemistry data and project management to streamline communication in Ohr’s R&D team.
  • Organize, present, and share data, challenges, questions, and strategies with Ohr’s global team.

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